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EN219
CAS No. : 380351-29-1
Biological Activity：EN219 is a moderately selective synthetic covalent ligand against an N-terminal cysteine (C8) of RNF114 with an IC50 of 470 nM. EN219 inhibits RNF114-mediated autoubiquitination and p21 ubiquitination.
Research Area：Cancer
Targets：E1/E2/E3 Enzyme
Related Small Molecules:UBE2T/FANCL-IN-1;p53 and MDM2 proteins-interaction-inhibitor (racemic);Navtemadlin;MD-224;DI-1859;MX69;RG7112;Teslexivir;TRAF6 peptide;AM-8735;NAcM-OPT;RO-5963;SENP1-IN-3;Avadomide;M435-1279;MI-1061;HB007;Ubiquitination-IN-1;Milademetan;Nutlin-3;NSC624206;Hydrocotarnine;TAK-243;PYR-41;SZL P1-41;Siremadlin;BRD5529;SMIP004
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