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Emodin-d4

CAS No. : 132796-52-2

Biological Activity：Emodin-d4 (Frangula emodin-d4) is the deuterium labeled Emodin. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects^[2]. Emodin is a potent selective 11β-HSD1 inhibitor with the IC₅₀ of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice^[3].

Research Area：Cancer

Targets：Autophagy|Casein Kinase|11β-HSD|SARS-CoV

Related Small Molecules:Umbralisib hydrochloride;BI-135585;SARS-CoV-2-IN-33;GRL-0496;Grazoprevir potassium salt;AZD8329;SARS-CoV-2-IN-19;Molnupiravir;ABT-384;SARS-CoV-2 Mpro-IN-3;MM3122;Ketotifen fumarate;4,5,6,7-Tetrabromo-1H-benzimidazole;SARS-CoV-2-IN-16;Thapsigargin;INSCoV-614(1B);(R)-BMS-816336;Anti-SARS-CoV-2 Spike mAb (CR3022);GNF-2;TA-01

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