Eltanexor Z-isomer

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Eltanexor Z-isomer

CAS No. : 1642300-78-4

Biological Activity:Eltanexor Z-isomer (KPT-8602 Z-isomer) is the less active isomer of KPT-8602. KPT-8602 is a potent CRM1 inhibitor.
IC50:
In Vitro: Eltanexor Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC50s of 100 nM-50 μM, < 100 nM, > 30 μM, respectively.
In Vivo:

Research Area:Cancer

Targets:CRM1

Related Screening Libraries:Bioactive Compound Library Plus;

Related Small Molecules:CRM1 degrader 1;Leptomycin A;PKF050-638;KPT-251;Leptomycin B

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