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Ebselen oxide

CAS No. : 104473-83-8

Biological Activity：Ebselen oxide, the selenone analogue of Ebselen, covalently modifies diguanylate cyclase (DGC) to inhibit c-di-GMP-receptor interactions and reduces DGC activity. Ebselen oxide also inhibits alginate production (IC₅₀=14 μM) by Pseudomonas aeruginosa. Ebselen oxide inhibits HDAC1, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, and HDAC9 (IC₅₀ ranging from 0.2 to 4.7 μM)^[2][3].

Research Area：Infection

Targets：Guanylate Cyclase

Related Small Molecules:Cinaciguat hydrochloride;Zagociguat;LY83583;Plecanatide;(4-Acetamidocyclohexyl) nitrate;N-Salicyloyltryptamine;Guanylin(human);BAY 41-2272;MGV354;NS-2028;BI 703704;Dolcanatide;Prepro-ANF (56-92), human;Nelociguat;Indusatumab;CFM 1571 hydrochloride;Cenderitide;BAY 41-8543;Ataciguat;MM 419447;Guanylate cyclase-IN-1;Praliciguat

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