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Dusquetide TFA
Biological Activity:Dusquetide (SGX942) TFA is a first-in-class innate defense regulator (IDR). Dusquetide TFA modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide TFA shows activity in both reducing inflammation and increasing clearance of bacterial infection. DAMPs: damage-associated molecular patterns; PAMPs: pathogen-associated molecular patterns
Research Area:Cancer|Infection
Targets:Bacterial
Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;Antibacterial agent 99;Nafcillin;Antitubercular agent-28;Ochromycinone;Staurosporine;Nucleocidin;(±)-Leucine-13C-1;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5;SQ109;Neomycin sulfate;Bauer-7-ene-3β,16α-diol;Aminothiazole
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Structurally and synthetically diverse biologically active compounds;
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