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Duocarmycin SA
CAS No. : 130288-24-3
Biological Activity：Duocarmycin SA is a potent antitumor antibiotic with an IC50 of 10 pM. Duocarmycin SA is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA. Duocarmycin SA demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells treated with proton radiation in vitro[2].
Research Area：Cancer
Targets：DNA Alkylator/Crosslinker|ADC Cytotoxin
Related Small Molecules:Sandramycin;(R)-Camptothecin-d5;Dolastatin 10;INX-SM-56;Anticancer agent 11;Tesirine;DC10SMe;Rebeccamycin;Duocarmycin TM;Fmoc-MMAE;Taltobulin;N-Me-L-Ala-maytansinol;CC-885-CH2-PEG1-NH-CH3;Camptothecin;Maytansinol;Tomaymycin DM;Prednimustine;Sibiromycin;Lurbinectedin;Hemiasterlin derivative-1;SGD-1882;Corixetan
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