Dronedarone D6 hydrochloride

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Dronedarone D6 hydrochloride

CAS No. : 1329809-23-5

Biological Activity:Dronedarone D6 hydrochloride is the deuterium labeled Dronedarone. Dronedarone hydrochloride, a derivative of Amiodarone (HY-14187), is a class III antiarrhythmic agent for the study of atrial fibrillation (AF) and atrial flutter. Dronedarone hydrochloride is a potent blocker of multiple ion currents, including potassium current, sodium current, and L-type calcium current, and exhibits antiadrenergic effects by noncompetitive binding to β-adrenergic receptors. Dronedarone hydrochloride is a substrate for and a moderate inhibitor of CYP3A4[2][3][4].

Research Area:Cardiovascular Disease

Targets:Adrenergic Receptor|Autophagy|Calcium Channel|mAChR|Sodium Channel|Cytochrome P450

Related Small Molecules:VU0357017 hydrochloride;Benidipine hydrochloride;SR9186;AMG-208;Lu AE98134;CaV1.3 antagonist-1;14-Deoxyandrographolide;Todralazine;TBPB;ARC 239 dihydrochloride;Imidafenacin;Zandatrigine;Sabcomeline;Yohimbine;(Rac)-MEM 1003;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;Glaucine;Veratridine;MK-6884;Efonidipine hydrochloride monoethanolate;Salbutamol

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