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Dooku1
CAS No. : 2253744-54-4
Biological Activity：Dooku1, an analog of Yoda1, is a selective antagonist of the endogenous Piezo1 channel. Dooku1 inhibited 2 μM Yoda1-induced Ca2+-entry with IC50 values of 1.3 μM (in HEK 293 cells) and 1.5 μM (in HUVECs). Dooku1 inhibits Yoda1-induced relaxation of aorta.
Research Area：Cardiovascular Disease
Targets：Piezo Channel
Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Anti-Cardiovascular Disease Compound Library;Mechanoreceptors Compound Library;
Related Small Molecules:GsMTx4 TFA;Yoda 1;Jedi2
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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