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Donepezil-d4 hydrochloride
CAS No. : 1219798-88-5
Biological Activity:Donepezil-d4 hydrochloride (E2020-d4) is the deuterium labeled Donepezil hydrochloride. Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM for AChE activity. Donepezil shows high selectivity for AChE over BuChE. Donepezil exhibits neuroprotective effect on Aβ42 neurotoxicity[2].
Research Area:Neurological Disease
Targets:Cholinesterase (ChE)
Related Small Molecules:Piperilate;BuChE-IN-5;AChE/BChE-IN-10;Timosaponin AIII;Trimyristin;AChE-IN-10;Isoimperatorin;Pseudocoptisine chloride;Itopride-d6 hydrochloride;Sinapine thiocyanate;sEH/AChE-IN-1;AChE-IN-11;Heliosupine;(-)-Cyclopenin;Leptomerine;eeAChE-IN-1;HDAC6-IN-6;Corydaline;Cyclanoline chloride;AChE-IN-20
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