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DM4-SPDP
CAS No. : 2245698-48-8
Biological Activity：DM4-SPDP is a drug-linker conjugate composed of a potent antitubulin agent DM4 and a linker SMCC to make antibody drug conjugate. SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls[2][3].
Research Area：Cancer
Targets：Microtubule/Tubulin|Drug-Linker Conjugates for ADC
Related Small Molecules:Tirbanibulin dihydrochloride;L-Asparagine-N-Fmoc,N-beta-trityl-15N2;Tilavonemab;Val-Cit-PAB-MMAF sodium;Tau tracer 1;MC-VC-PABC-SP 141;Dolastatin 10;Deruxtecan analog 2;PSMA-ALB-56;Gly3-VC-PAB-MMAE;Ceratamine A;MP-PEG8-Val-Lys-Gly-7-MAD-MDCPT;Batabulin sodium;OXi8007;Tesirine;Antitumor agent-68;Dictyostatin;Tubulin inhibitor 6;Oryzalin;SPB;Tubulin inhibitor 25;Fmoc-MMAE;Taltobulin;(Rac)-Lys-SMCC-DM1;Tubulin inhibitor 16;Epothilone B
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