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Dihydroergocristine mesylate
CAS No. : 24730-10-7
Biological Activity：Dihydroergocristine mesylate (DHEC mesylate) is a inhibitor of γ-secretase (GSI), reduces the production of the Alzheimer’s disease amyloid-β peptides, binds directly to γ-secretase and Nicastrin with equilibrium dissociation constants (Kd) of 25.7 nM and 9.8 μM, respectively.
Research Area：Neurological Disease
Targets：Amyloid-β
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Neuronal Signaling Compound Library;FDA-Approved Drug Library;Drug Repurposing Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Alzheimer’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;
Related Small Molecules:β-Amyloid (13-27);Saikosaponin C;β-Amyloid (1-42), (rat/mouse) (TFA);β-Amyloid (12-28) (TFA);BuChE-IN-5;Ginsenoside Rg1;MDR-1339;β-Amyloid (11-22);20(S)-Ginsenoside Rg3;β-Amyloid (31-35);Aβ-IN-1;Qingyangshengenin B;JNJ-40418677;HDAC6-IN-6;β-Amyloid (1-37) (human);CGP52411;Astrophloxine;γ-Secretase modulator 12;δ-Secretase inhibitor 11;BuChE-IN-2;FPS-ZM1;BChE-IN-8;4-(6-Bromo-2-benzothiazolyl)benzenamine;Timosaponin BII;Valiltramiprosate;Azeliragon;CRANAD-2
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