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[D-Trp8]-γ-MSH

CAS No. : 321351-81-9

Biological Activity：[D-Trp8]-γ-MSH is a potent and selective agonist of melanocortin 3 (MC3) receptor, with IC₅₀s of 6.7 nM, 600 nM and 340 nM for hMC3, hMC4 and hMC5, respectively in CHO cells. [D-Trp8]-γ-MSH could provide protection against multiple inflammatory disorders such as rheumatoid arthritis and colitis^[2].

Research Area：Inflammation/Immunology

Targets：Melanocortin Receptor

Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Neuronal Signaling Compound Library;Anti-Obesity Compound Library;Peptide Library;

Related Small Molecules:Bremelanotide;MSG606 TFA;Resomelagon;Dersimelagon;Adrenocorticotropic Hormone (ACTH) (1-39), rat TFA;Terrein;γ1-MSH TFA;SNT-207707;PF-07258669;THIQ;ACTH (11-24) (acetate);JKC363 TFA;PG-931 TFA;MC-4R Agonist 1;ACTH (1-17);SNT-207858 free base;Lys-γ3-MSH(human);Nonapeptide-1;HS024 TFA;Adrenocorticotropic Hormone (ACTH) (4-10), human;SHU 9119;Adrenocorticotropic Hormone (ACTH) (1-39), human(TFA);(p-Iodo-Phe7)-ACTH (4-10)

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