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Cynaropicrin
CAS No. : 35730-78-0
Biological Activity：Cynaropicrin is a sesquiterpene lactone which can inhibit tumor necrosis factor (TNF-α) release with IC50s of 8.24 and 3.18 μM for murine and human macrophage cells, respectively. Cynaropicrin also inhibits the increase of cartilage degradation factor (MMP13) and suppresses NF-κB signaling.
Research Area：Cancer
Targets：TNF Receptor|NF-κB|MMP
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