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CRM1 degrader 1
Biological Activity：CRM1 degrader 1 (1l) is a low toxic chromosome region maintenance 1 (CRM1) degrader. CRM1 is the sole nuclear exporter of several tumor suppressor, a growth regulatory protein as an attractive cancer drug target. CRM1 degrader 1 induces the apoptosis in gastric carcinoma and selectively inhibits proliferation of gastric cancer.
Research Area：Cancer
Targets：CRM1
Related Small Molecules:Eltanexor Z-isomer;Leptomycin A;PKF050-638;KPT-251;Leptomycin B
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Structurally and synthetically diverse biologically active compounds；
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