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Clemizole hydrochloride

CAS No. : 1163-36-6

Biological Activity：Clemizole hydrochloride is an H1 histamine receptor antagonist, is found to substantially inhibit HCV replication. Clemizole hydrochloride is an inhibitor of TRPC5 channel. The IC₅₀ of Clemizole hydrochloride for RNA binding by NS4B is 24 nM, whereas its EC₅₀ for viral replication is 8 µM.

Research Area：Cancer|Inflammation/Immunology|Endocrinology

Targets：HCV|HCV Protease|TRP Channel|Histamine Receptor

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Membrane Transporter/Ion Channel Compound Library;Metabolism/Protease Compound Library;Neuronal Signaling Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Drug Repurposing Compound Library;Endocrinology Compound Library;Orally Active Compound Library;Neurotransmitter Receptor Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Hepatitis C Virus Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Mechanoreceptors Compound Library;Targeted Diversity Library;Rare Diseases Drug Library;FDA-Approved Anticancer Drug Library;Coagulation and Anti-coagulation Compound Library;

Related Small Molecules:V116517;GSK2332255B;Pregnenolone monosulfate sodium;HCV-IN-30;NS5A-IN-1;TRPC5-IN-4;HCV-IN-38;Tripelennamine;OptoBI-1;Brompheniramine-d6 maleate;Sennidin A;Samelisant;SB-705498;Chlorphenoxamine;HCV-IN-31;Radalbuvir;Grazoprevir potassium salt;FGI-106 tetrahydrochloride;H3 receptor-MO-1;Diphenhydramine;TRPC3/6-IN-1;ABT-239;BMS-986144;Pyr3

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