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Clarithromycin
CAS No. : 81103-11-9
Biological Activity：Clarithromycin has a broad spectrum of antimicrobial activity. Clarithromycin inhibits the CYP3A4-catalyzed triazolam alpha-hydroxylation with the IC50 (Ki) value of 56 (43) μM[2]. Clarithromycin significantly inhibits the HERG potassium current[3].Clarithromycin affects the autophagic flux by impairing the signaling pathway linking hERG1 and PI3K[4].
Research Area：Infection|Cancer
Targets：Autophagy|Bacterial|Antibiotic|Cytochrome P450
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