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Cintirorgon
CAS No. : 2055536-64-4
Biological Activity：Cintirorgon (LYC-55716) is a first-in-class, selective and orally bioavailable RORγ agonist. Cintirorgon (LYC-55716) modulates gene expression of RORγ expressing T lymphocyte immune cells, resulting in enhanced effector function, as well as decreased immunosuppression, resulting in decreased tumor growth, and improved survival[2].
Research Area：Cancer
Targets：ROR
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Small Molecule Immuno-Oncology Compound Library;Drug Repurposing Compound Library;Orally Active Compound Library;Transcription Factor-Targeted Library;Nuclear Receptor Compound Library;
Related Small Molecules:RORγt inhibitor 1;GNE-6468;SR3335;RORγt inverse agonist 30;GNE-0946;RORγt inverse agonist 13;Vimirogant hydrochloride;SR2211;Bevurogant;ROR agonist-1;RORγt Inverse agonist 8;CD12681;S18-000003;RORγt inhibitor 2;XY018;RORγt inverse agonist 29;SR1001;Cedirogant;SHR168442;ARN-6039;A-9758;Nobiletin;TAK-828F;RORγt inverse agonist 26;GSK805;PF-06747711;Zilovertamab;(±)-ML 209
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