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CHIC35
CAS No. : 848193-72-6
Biological Activity:CHIC35, an analog of EX-527, is a potent and selective inhibitor of SIRT1 (IC50=0.124 µM). CHIC35 shows potential selective inhibition against SIRT1 over SIRT2 (IC50=2.8 µM) or SIRT3 (IC50>100 µM). CHIC35 has anti-inflammatory effects and can be used for CHARGE syndrome research[2].
Research Area:Inflammation/Immunology|Neurological Disease
Targets:Sirtuin
Related Small Molecules:PROTAC Sirt2 Degrader-1;SIRT1/2/3-IN-1;Cambinol;JGB1741;Nicotinamide-d4;Sirtuin modulator 3;Resveratrol;SRT 1720 Hydrochloride;Sirtuin modulator 2;SIRT1-IN-3;SRT 2104;Tenovin-6;SirReal2;Ganoderic acid D;MC3482;Dihydrocoumarin;AK-1;SIRT2-IN-9;JFD00244;OSS_128167;Inauhzin;SRT 2183;SRTCX1002;Nicotinamide riboside;3-TYP;SIRT-IN-2;SIRT1 activator 3;SRT3657;Resveratrol-d4
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