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Cerivastatin
CAS No. : 145599-86-6
Biological Activity：Cerivastatin is a synthetic lipid-lowering agent and a highly potent, well-tolerated and orally active HMG-CoA reductase inhibitor, with a Ki of 1.3 nM/L. Cerivastatin reduces low-density lipoprotein cholesterol levels. Cerivastatin also inhibits proliferation and invasiveness of MDA-MB-231 cells, mainly by RhoA inhibition, and has anti-cancer effect[2][3].
Research Area：Cancer|Cardiovascular Disease
Targets：Ferroptosis|HMG-CoA Reductase (HMGCR)
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