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CCB02
CAS No. : 2100864-57-9
Biological Activity:CCB02 is a selective CPAP-tubulin interaction inhibitor, binding to tubulin and competing for the CPAP binding site of β-tubulin, with an IC50 of 689 nM, and shows potent anti-tumor activity. CCB02 shows no inhibition on the cell cycle- and centrosome-related kinases, or the phosphorylation status of Aurora A, Plk1, Plk2, CDK2, and CHK1.
Research Area:Cancer
Targets:Microtubule/Tubulin
Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Cytoskeleton Compound Library;Anti-Lung Cancer Compound Library;Targeted Diversity Library;Protein-protein Interaction Inhibitor Library;
Related Small Molecules:Tirbanibulin dihydrochloride;Tilavonemab;Tau tracer 1;Dolastatin 10;Ceratamine A;Batabulin sodium;OXi8007;Antitumor agent-68;Dictyostatin;Tubulin inhibitor 6;Oryzalin;Tubulin inhibitor 25;Fmoc-MMAE;Taltobulin;Tubulin inhibitor 16;Epothilone B;TN-16;Maytansinol;VcMMAE;Mc-MMAE;SS28;Tubulysin H;Fosbretabulin disodium;Tubulin polymerization-IN-7
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