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Carmofur

CAS No. : 61422-45-5

Biological Activity：Carmofur (HCFU), a derivative of 5-Fluorouracil, is an antineoplastic agent. Carmofur is an inhibitor of acid ceramidase with an IC₅₀ of 79 nM for the rat enzyme. Carmofur inhibits the SARS-CoV-2 main protease (Mpro). Carmofur Inhibits SARS-CoV-2 in Vero E6 cell with an EC₅₀ of  24.3  μM^[2].

Research Area：Cancer

Targets：Nucleoside Antimetabolite/Analog|Virus Protease|SARS-CoV

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Cell Cycle/DNA Damage Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Reprogramming Compound Library;Anti-COVID-19 Compound Library;NMPA-Approved Drug Library;FDA Approved & Pharmacopeial Drug Library;Anti-Lung Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Lipid Metabolism Compound Library ;FDA-Approved Anticancer Drug Library;Human Metabolite Library;

Related Small Molecules:SRPIN340;ZIKV-IN-4;m7GpppCpG;7-TFA-ap-7-Deaza-dA;Aminothiazole;CYP2C9/CYP2C19-IN-1;SARS-CoV-2-IN-33;m7GpppUmpG;GRL-0496;DMT-2′-F-Bz-dA;Grazoprevir potassium salt;SARS-CoV-2-IN-19;Molnupiravir;Cytidine-d1;SARS-CoV-2 Mpro-IN-3;Dmt-2′-f-dc(ac) amidite;Uridine 13C-1;L-Lysine

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