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Brexpiprazole
CAS No. : 913611-97-9
Biological Activity：Brexpiprazole (OPC-34712), an atypical orally active antipsychotic drug, is a partial agonist of human 5-HT1A and dopamine D2L receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM. Brexpiprazole also shows potent antagonist activity at human noradrenergic α1B (Ki=0.17 nM) and α2C receptors (Ki=0.59 nM)[2].
Research Area：Neurological Disease
Targets：Dopamine Receptor|Adrenergic Receptor|5-HT Receptor
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;FDA-Approved Drug Library;Drug Repurposing Compound Library;Orally Active Compound Library;Neurotransmitter Receptor Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Alzheimer’s Disease Compound Library;Anti-Parkinson’s Disease Compound Library;Anti-Obesity Compound Library;Children’s Drug Library;Antidepressant Compound Library;EMA-Approved Drug Library;5-HT Receptor Compound Library;Human Metabolite Library;Coagulation and Anti-coagulation Compound Library;
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