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BRD5529
CAS No. : 1358488-78-4
Biological Activity：BRD5529 is an effective dose-dependent CARD9-TRIM62 protein–protein interaction (PPI) inhibitor with an IC50 value of 8.6 μM. BRD5529 has potency and complete inhibition of CARD9 ubiquitinylation in vitro, also has favorable solubility. BRD5529 can be used for the research of inflammatory bowel disease (IBD) such as Crohn’s disease (CD) and ulcerative colitis (UC)[2].
Research Area：Infection|Inflammation/Immunology
Targets：E1/E2/E3 Enzyme
Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Oxygen Sensing Compound Library;Ubiquitination Compound Library;Targeted Diversity Library;Anti-Liver Cancer Compound Library ;
Related Small Molecules:UBE2T/FANCL-IN-1;p53 and MDM2 proteins-interaction-inhibitor (racemic);Navtemadlin;MD-224;DI-1859;MX69;RG7112;Teslexivir;TRAF6 peptide;AM-8735;NAcM-OPT;RO-5963;SENP1-IN-3;Avadomide;M435-1279;MI-1061;HB007;Ubiquitination-IN-1;Milademetan;EN219;Nutlin-3;NSC624206;Hydrocotarnine;TAK-243;PYR-41;SZL P1-41;Siremadlin;SMIP004
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