For research use only. We do not sell to patients.

BRD4770

CAS No. : 1374601-40-7

Biological Activity：BRD4770 is a histone methyltransferase G9a inhibitor. BRD4770 reduces di- and trimethylation of lysine 9 on histone H3 (H3K9) with an EC₅₀ of 5 µM, and has less or little effect toward H3K27me3, H3K36me3, H3K4me3, and H3K79me3. BRD4770 can activate the ataxia telangiectasia mutated (ATM) pathway and induce cell senescence.

Research Area：Cancer

Targets：Histone Methyltransferase

Related Screening Libraries:Bioactive Compound Library Plus;Epigenetics Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Reprogramming Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;

Related Small Molecules:EEDi-5285;EZH2-IN-2;BIX-01294;SGC707;(S)-HH2853;G9a-IN-1;UNC4976;MS1943;OTS186935 hydrochloride;MS8815;(R)-HH2853;EPZ020411;Furamidine dihydrochloride;EZH2-IN-12;UNC0642;MU1656;Chaetocin;UNC0646;UNC0224;MRK-740;SMYD2-IN-1;PRMT5-IN-21;Sinefungin;MM-401;SETDB1-TTD-IN-1;Dot1L-IN-2;PRMT5-IN-10;PRMT1-IN-1

About Us:

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
Structurally and synthetically diverse biologically active compounds；
roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；

Structurally and synthetically diverse biologically active compounds；

Customized order volume ranging from milligrams to kilograms scale；

We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.

Top Publications Citing Use of MCE Products