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BRD0209
CAS No. : 1597439-87-6
Biological Activity：BRD0209 is a potent, selective and dual inhibitor of GSK3α/β inhibitor (GSK3α IC50 = 19 nM; GSK3β IC50 = 5 nM). BRD0209 is also a reversible ATP-competitive inhibitor with fast-off kinetics (Ki = 4.2 nM, respectively). BRD0209 is a tricyclic pyrazolotetrahydroquinolinone compound. BRD0209 has the potential for the research of mood disorder diseases.
Research Area：Neurological Disease
Targets：GSK-3
Related Small Molecules:TCS2002;AR-A014418;GSK 3 Inhibitor IX;MeBIO;Cromolyn-d5 sodium;GS87;ZDWX-25;ARN25068;PfGSK3/PfPK6-IN-2;RGB-286638;Laduviglusib (GMP);GSK3 Substrate, α, β subunit;DIF-3;Bikinin;A 1070722;Indirubin-3′-monoxime;Indirubin-5-sulfonate;Aloisine RP106;GNF4877;Indirubin-3′-monoxime-5-sulphonic acid;ABC1183;GSK-3β inhibitor 10;Cromolyn sodium;AZD1080;TCS 21311;KY19382;CHIR-98014;SB 415286
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