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BMS-986158
CAS No. : 1800340-40-2
Biological Activity:BMS-986158 is a potent BET inhibitor with IC50s of 6.6 and 5 nM in NCI-H211 small cell lung cancer (SCLC) cells and MDA-MB231 triple negative breast cancer (TNBC) cells, respectively.
Research Area:Cancer
Targets:Epigenetic Reader Domain
Related Screening Libraries:Covalent Screening Library Plus;Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Epigenetics Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Covalent Screening Library;Reprogramming Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Blood Cancer Compound Library;
Related Small Molecules:RVX-297;BRD4 Inhibitor-19;UNC6349 (Ket2);Curcumin;GSK6853;GSK4028;SR-0813;Inobrodib;Apabetalone;OF-1;I-CBP112;A-485;PLX51107;FKBP12 PROTAC dTAG-7;I-BET151;GSK040;BRM/BRG1 ATP Inhibitor-4;PBRM1-BD2-IN-5;MI-136;IACS-9571;SF2523;L-Moses dihydrochloride;KB02-JQ1;GSK620;INCB-057643;Bromodomain IN-1;QCA570;BRM/BRG1 ATP Inhibitor-1;Ziftomenib
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