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BI-4924
CAS No. : 2244452-09-1
Biological Activity：BI-4924 is a lipophilic, highly plasma protein bound selective phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50=3 nM) with excellent microsomal, as well as hepatocytic stability. Intracellular trapping of BI-4924 disrupts serine biosynthesis with an IC50 of 2200 nM at 72 h.
Research Area：Cancer
Targets：Phosphoglycerate Dehydrogenase (PHGDH)
Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Targeted Diversity Library;
Related Small Molecules:NCT-502;BI-4916;PHGDH-inactive;NCT-503;CBR-5884
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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