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Aurora/LIM kinase-IN-1
Biological Activity：Aurora/LIM kinase-IN-1 (Compound F114) is a potent and dual inhibitor of aurora and lim kinase. Aurora kinases and lim kinases are involved in neoplastic cell division and cell motility, respectively. Aurora/LIM kinase-IN-1 inhibits GBM proliferation and invasion. Aurora/LIM kinase-IN-1 is a promising new scaffold for dual aurora/lim kinase inhibitors that may be used in future drug development efforts for GBM, and potentially other cancers.
Research Area：Cancer
Targets：Aurora Kinase|LIM Kinase (LIMK)
Related Small Molecules:DB0614;AT9283;Chiauranib;CRT0105950;ENMD-2076 Tartrate;Barasertib-HQPA;AMG 900;SCH-1473759;BI-847325;BMS-3;CCT129202;PF 477736;CD532;ZM-447439;Palmatine;TAK-632;SM1-71;MK-8745;NU6140;Aurora kinase inhibitor-9;Aurora A inhibitor 1;Aurora Kinases-IN-2;Ilorasertib;PHA-680632;TH470;Aurora inhibitor 1;Hesperadin;Tozasertib;Alisertib;R-10015
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