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ATM Inhibitor-1

CAS No. : 2135639-94-8

Biological Activity：ATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibitor, with an IC₅₀ of 0.7 nM, shows weak activity against mTOR (IC₅₀, 21 μM), DNAPK (IC₅₀, 2.8 μM), PI3Kα (IC₅₀, 3.8 μM), PI3Kβ (IC₅₀, 10.3 μM), PI3Kγ (IC₅₀, 3 μM) and PI3Kδ (IC₅₀, 0.73 μM). ATM Inhibitor-1 exhibits anti-tumor activity.

Research Area：Cancer

Targets：ATM/ATR

Related Small Molecules:ATR-IN-16;ATR-IN-4;CGK733;Ceralasertib;KU 59403;ATR-IN-5;ATR inhibitor 1;VE-821;KU-55933;Garcinone C;SKLB-197;ATR-IN-18;AZD0156;CP-466722;Mirin;ATR-IN-13;Antitumor agent-28;ATR-IN-11;ATR-IN-8;AZ31;ATR-IN-12;ATR-IN-20;ATM Inhibitor-2;Elimusertib;Ro 90-7501;Gartisertib;ATR-IN-7;ATR-IN-17;KU-60019

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