Atg4B-IN-2

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Atg4B-IN-2

CAS No. : 2765008-88-4

Biological Activity:Atg4B-IN-2 is a potent competitive Atg4B inhibitor with Ki value of 3.1 μM, also possesses declining PLA2 inhibitory potency, IC50s of 11 μM and 3.5 μM for Atg4B and PLA2, respectively. Atg4B-IN-2 enhances the anticancer activity of anti-castration-resistant prostate cancer drugs via autophagy inhibition.

Research Area:Cancer

Targets:Cathepsin|Autophagy|Phospholipase

Related Small Molecules:GK563;Calpeptin;DPTIP;Cambinol;Neomycin sulfate;Cathepsin G Inhibitor I;ONO-RS-082;Gly-Phe-β-naphthylamide;ARN19874;LEI-401;ST271;Melittin TFA;Z-FY-CHO;(S)-Bromoenol lactone;Balicatib;GK187;D-Erythro-dihydrosphingosine-d7;FKGK11;PACOCF3;DL-erythro-Dihydrosphingosine;1-Naphthaleneacetic acid potassium salt;C12 NBD Sphingomyelin;Cathepsin D and E FRET Substrate;N-CBZ-Phe-Arg-AMC TFA;ML-298;LV-320;sPLA2-X Inhibitor 31

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