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APX-115 free base
CAS No. : 1270084-92-8
Biological Activity:APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 free base effectively prevents kidney injury.
Research Area:Endocrinology|Inflammation/Immunology
Targets:NADPH Oxidase
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Anti-diabetic Compound Library;Oxygen Sensing Compound Library;Endocrinology Compound Library;Ferroptosis Compound Library;Orally Active Compound Library;Glutamine Metabolism Compound Library;Anti-Cancer Metabolism Compound Library;Glucose Metabolism Compound Library;Targeted Diversity Library;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:GKT136901;VAS2870;VAS 3947;NoxA1ds;Diphenyleneiodonium chloride;GSK2795039;Setanaxib;Mulberrofuran G;Fulvene-5;Fluoflavine;GLX351322;ML171
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