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Apremilast-d5

CAS No. : 1258597-47-5

Biological Activity：Apremilast D5 (CC-10004 D5) is a deuterium labeled Apremilast. Apremilast is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC₅₀ of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC₅₀ of 104 nM.

Research Area：Inflammation/Immunology

Targets：Phosphodiesterase (PDE)|TNF Receptor|Apoptosis

Related Small Molecules:Physalin A;Bomedemstat ditosylate;Senazodan hydrochloride;(E/Z)-HA155;Akt/NF-κB/JNK-IN-1;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;AX-024;ATX inhibitor 22;Carbazeran citrate;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Bay 60-7550

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