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Amustaline dihydrochloride
CAS No. : 210584-54-6
Biological Activity:Amustaline (S-303) dihydrochloride, a nucleic acid-targeted alkylator, is an efficient pathogen inactivation agent for blood components containing red blood cells. Amustaline dihydrochloride has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products)[2].
Research Area:Infection
Targets:HIV|Bacterial
Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;HIV-1 TAT (48-60);Antibacterial agent 99;Nafcillin;Antitubercular agent-28;Ochromycinone;Seletracetam lithium;Staurosporine;HIV-IN-2;Nucleocidin;(±)-Leucine-13C-1;Ciclopirox-d11
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