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AM-6494

CAS No. : 1874232-80-0

Biological Activity：AM-6494 is a potent and orally active BACE1 (efficacious β-site amyloid precursor protein cleaving enzyme 1) inhibitor (IC₅₀=0.4 nM) with in vivo selectivity over BACE2 (IC₅₀=18.6 nM).

Research Area：Neurological Disease

Targets：Beta-secretase

Related Small Molecules:LY2886721;BACE1-IN-9;β-Secretase Inhibitor II;Cassiaside;Glabrolide;OM99-2;JNJ-67569762;β-Secretase Inhibitor III;BACE1-IN-12;BACE1-IN-11;Multitarget AD inhibitor-1;BACE-1 inhibitor 1;BACE1-IN-8;LX2343;LY2811376;COX-2-IN-22;AZD3839 free base;Aloenin;β-Secretase Inhibitor IV;AChE/BChE/BACE-1-IN-2;BACE1-IN-4;Sophoflavescenol;Aloeresin D;BACE-IN-1;BACE-1 inhibitor 2;Epiberberine chloride;BACE1-IN-2

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