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Allopurinol
CAS No. : 315-30-0
Biological Activity：Allopurinol is a potent and orally active xanthine oxidase inhibitor with an IC50 value of 0.2-50 µM. Allopurinol can be used in the treatment of hyperuricemia and gout. Allopurinol decreases the expression of HIF-1α and HIF-2α protein. Allopurinol shows anti-depressant and anti-nociception activity. Anti-leishmanial effect[2][3][4][5].
Research Area：Cancer|Infection|Inflammation/Immunology|Neurological Disease
Targets：Xanthine Oxidase
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Nucleotide Compound Library;Oxygen Sensing Compound Library;Anti-COVID-19 Compound Library;NMPA-Approved Drug Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Targeted Diversity Library;Rare Diseases Drug Library;Children’s Drug Library;EMA-Approved Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Non-steroidal Anti-Inflammatory Compound Library;
Related Small Molecules:Lobetyolin;Xanthine oxidase-IN-4;Prudomestin;Morin 3-O-β-D-glucopyranoside;Xanthine oxidase-IN-9;Xanthine oxidoreductase-IN-4;XO/COX/LOX-IN-1;Xanthine oxidase-IN-6;Topiroxostat;Xanthine oxidase-IN-8;Xanthine oxidoreductase-IN-1;Benzbromarone-d5;Xanthine oxidase-IN-1;Oxypurinol;Forsythoside F;Flazin;Xanthine oxidase-IN-5;Xanthine oxidoreductase-IN-3;Phytic acid dodecasodium hydrate;Benzbromarone;Ilexoside O;Nequinate;H-Tyr-Phe-OH
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