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ALK-IN-22

CAS No. : 2468219-09-0

Biological Activity：ALK-IN-22 (compound I-24) is a potent ALK inhibitor with IC₅₀ values of 2.3, 3.7 and 2.9 nM for ALK, ALK^L1196M and ALK^G1202R, respectively. ALK-IN-22 down-regulated the phosphorylation of ALK and its downstream proteins. ALK-IN-22 induces apoptosis. ALK-IN-22 can be used for tumor research.

Research Area：Cancer

Targets：Anaplastic lymphoma kinase (ALK)|Apoptosis

Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;ALK-IN-9;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D;STAT3-IN-10

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