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Alicapistat
CAS No. : 1254698-46-8
Biological Activity:Alicapistat (ABT-957) is an orally active selective inhibitor of human calpains 1 and 2 for the potential application of Alzheimer’s disease (AD). Alicapistat mitigates the metabolic liability of carbonyl reduction and inhibits calpain 1 with an IC50 value of 395 nM[2].
Research Area:Neurological Disease
Targets:Proteasome
Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;
Related Small Molecules:Calpeptin;Calpain Inhibitor VI;MG-101;ONX-0914 TFA;MG-115;UK-101;SAP2-IN-1;LXE408;GSK3494245;PR-39;20S Proteasome-IN-1;M3258;PI-1840;Rpn11-IN-1;Delanzomib;Ac-ANW-AMC;Cyclotheonellazole A;Aclacinomycin A;Vimentin-IN-1;DD1;VR23;Tomatine;Gabexate mesylate;Neurodegenerative Disorder-Targeting Compound 1
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