6-Thioguanine

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6-Thioguanine

CAS No. : 154-42-7

Biological Activity:6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively.

Research Area:Cancer|Infection|Inflammation/Immunology

Targets:Autophagy|Deubiquitinase|DNA Methyltransferase|Endogenous Metabolite|Apoptosis|SARS-CoV

Related Screening Libraries:Covalent Screening Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound Library;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Covalent Screening Library;Reprogramming Compound Library;Nucleotide Compound Library;Ubiquitination Compound Library;Anti-COVID-19 Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Blood Cancer Compound Library;Transcription Factor-Targeted Library;Rare Diseases Drug Library;Children’s Drug Library;Chemotherapy Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;

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