For research use only. We do not sell to patients.
YM458
Biological Activity:YM458 is a potent EZH2 and BRD4 dual inhibitor with IC50s of 490 nM and 34 nM, respectively. YM458 inhibits cell proliferation and colony formation and induces cell cycle arrest and apoptosis in solid cancer cells. YM458 can be used for researching anticancer.
Research Area:Cancer
Targets:Epigenetic Reader Domain|Histone Methyltransferase|Apoptosis
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;RVX-297;Lobetyolin;BRD4 Inhibitor-19;EEDi-5285;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;EZH2-IN-2;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;UNC6349 (Ket2);Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5
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Structurally and synthetically diverse biologically active compounds;
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