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YM-53601 free base

CAS No. : 182959-28-0

Biological Activity：YM-53601 free base, a squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in vivo. YM-53601 free base inhibits squalene synthase derived from human hepatoma cells with an IC₅₀ of 79 nM. Lipid-lowering agent^[2]. YM-53601 free base is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) enzyme activity and abrogates HCV propagation^[3].

Research Area：Metabolic Disease

Targets：HCV|Farnesyl Transferase

Related Small Molecules:HCV-IN-30;HCV-IN-38;Sennidin A;HCV-IN-31;Radalbuvir;Grazoprevir potassium salt;FGI-106 tetrahydrochloride;BMS-986144;Oenothein B;Triton X-45(n=4);Mecarbinate;Artemisinin-d3;TTP-8307;HCV-IN-34;Miravirsen;Ciluprevir;ABT-100;MK-0608;Setrobuvir;Astodrimer;Elbasvir

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