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VZ185

CAS No. : 2306193-61-1

Biological Activity：VZ185 is a potent, fast, and selective von Hippel-Lindau based dual degrader probe of BRD9 and BRD7 with DC₅₀s of 4.5 and 1.8 nM, respectively. VZ185 is cytotoxic in EOL-1 and A-402 cells, with EC₅₀s of 3 nM and 40 nM, respectively.

Research Area：Cancer

Targets：Epigenetic Reader Domain|PROTACs

Related Screening Libraries:Bioactive Compound Library Plus;Epigenetics Compound Library;Histone Modification Research Compound Library;Anti-Cancer Compound Library;Reprogramming Compound Library;Chemical Probe Library;Anti-Blood Cancer Compound Library;Targeted Diversity Library;

Related Small Molecules:PROTAC Sirt2 Degrader-1;DB0614;RVX-297;BRD4 Inhibitor-19;UNC6349 (Ket2);PROTAC VEGFR-2 degrader-2;Curcumin;GSK6853;dTAGV-1-NEG;CCT367766 formic;GSK4028;SR-0813;HDAC6 degrader-1;PROTAC Axl Degrader 2;Inobrodib;PhosTAC7;MS98;Apabetalone;OF-1;I-CBP112;JPS014;PROTAC PARP1 degrader;A-485;MD-224;PLX51107;FKBP12 PROTAC dTAG-7;I-BET151;SJ10542;MS8815;GSK040

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