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Toceranib-d8
CAS No. : 1795134-78-9
Biological Activity：Toceranib-d8 (SU11654-d8) is the deuterium labeled Toceranib. Toceranib (SU11654) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively. Toceranib (SU11654) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors[2].
Research Area：Cancer
Targets：VEGFR|c-Kit|PDGFR
Related Small Molecules:(Z)-FeCP-oxindole;VEGFR-2-IN-24;BMS-690514;PROTAC VEGFR-2 degrader-2;Henatinib;PI3K/VEGFR2-IN-1;c-Kit-IN-5-1;Flumatinib mesylate;IHMT-TRK-284;PDGFRα/FLT3-ITD-IN-2;PP58;Hydroxytanshinone IIA;Chiauranib;Foretinib;ZM323881 hydrochloride;Zeteletinib;Pexidartinib;PTC299;ENMD-2076 Tartrate;Aflibercept;SU5408;MAZ51;R1530
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