THK-5105

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THK-5105

CAS No. : 1374107-46-6

Biological Activity:THK-5105, an arylquinoline derivative, displays high binding affinity to tau fibrils. THK-5105 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD)  brain homogenates. 18F-THK-5105 has the potential to act as a tau imaging PET probe.

Research Area:Neurological Disease

Targets:Microtubule/Tubulin

Related Small Molecules:Tirbanibulin dihydrochloride;Tilavonemab;Tau tracer 1;Dolastatin 10;Ceratamine A;Batabulin sodium;OXi8007;Antitumor agent-68;Dictyostatin;Tubulin inhibitor 6;Oryzalin;Tubulin inhibitor 25;Fmoc-MMAE;Taltobulin;Tubulin inhibitor 16;Epothilone B;TN-16;Maytansinol;VcMMAE;Mc-MMAE;SS28;Tubulysin H;Fosbretabulin disodium;Tubulin polymerization-IN-7

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