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TH5487

CAS No. : 2304947-71-3

Biological Activity：TH5487 is a potent 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor with an IC₅₀ of 342 nM. TH5487 stops OGG1 from recognizing its DNA substrate, inhibits DNA repair and modifies OGG1 chromatin dynamics, which results in the inhibition of proinflammatory pathway genes.

Research Area：Inflammation/Immunology

Targets：Others

Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Targeted Diversity Library;

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