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RWJ-67657
CAS No. : 215303-72-3
Biological Activity：RWJ-67657 (JNJ 3026582) is an orally active and selective p38α and p38β MAPK inhibitor with IC50s of 1 and 11 μM, respectively. RWJ-67657 displays no activity at p38γ and p38δ, and exhibits cardio protective effect. Anti-inflammatory and anti-tumor activity.
Research Area：Cancer|Inflammation/Immunology|Cardiovascular Disease
Targets：p38 MAPK
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;MAPK Compound Library;Anti-Cancer Compound Library;Reprogramming Compound Library;Anti-diabetic Compound Library;Oxygen Sensing Compound Library;Anti-Cardiovascular Disease Compound Library;Pyroptosis Compound Library;Anti-Lung Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Targeted Diversity Library;Antidepressant Compound Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:SB-747651A dihydrochloride;Dehydrocorydaline;SKF-86002 dihydrochloride;Pexmetinib;SB 242235;TA-01;Anti-inflammatory agent 7;MW-150;VX-702;R1487 Hydrochloride;MBP MAPK Substrate;Isoliquiritin apioside;Sesamolin;MAPK13-IN-1;PF-05381941;Semapimod tetrahydrochloride;SD-169;Skatole;BMS-582949 hydrochloride;Gypenoside L;Dilmapimod;Pamapimod;Andrograpanin;MKK7-COV-9;AMG-47a;Kaempferol-3-O-glucorhamnoside;SB 202190 hydrochloride
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