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RUSKI-201 dihydrochloride
CAS No. : 2320262-09-5
Biological Activity：RUSKI-201 dihydrochloride is a potent and specific Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 0.20 μM. RUSKI-201 dihydrochloride is able to block Hh signaling from Shh overexpressing cells and inhibits Hh palmitoylation. RUSKI-201 dihydrochloride is potential Hhat chemical probe in cells and can used in studies of Hhat catalytic function.
Research Area：Cancer
Targets：Hedgehog
Related Small Molecules:RU-SKI 43;Dynarrestin;RL-0070933;SANT 2;Ciliobrevin D;TPB15;CUR61414;HSP70-IN-3;SANT-1;Hh-Ag1.5;SMANT hydrochloride;Robotnikinin;Ciliobrevin A;SMO-IN-2;JK184;MK-4101;3-epi-Vitamin D3;Neurodazine;TAK-441;Jervine;SMO-IN-3
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