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RSVA405
CAS No. : 140405-36-3
Biological Activity:RSVA405 is a potent, orally active activator of AMPK, with an EC50 of 1 μM. RSVA405 facilitates CaMKKβ-dependent activation of AMPK, inhibits mTOR, and promotes autophagy to increase Aβ degradation. RSVA405 has anti-inflammatory effects through the inhibition of STAT3 function. RSVA405 can also be used for the research of obesity[2][3][4].
Research Area:Metabolic Disease|Inflammation/Immunology|Neurological Disease
Targets:Autophagy|STAT|AMPK
Related Screening Libraries:Bioactive Compound Library Plus;Epigenetics Compound Library;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Oxygen Sensing Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;Lipid Metabolism Compound Library ;Glucose Metabolism Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:AMPK activator 4;Cirsilineol;Ochromycinone;C188-9;STAT3-IN-10;C188;Niclosamide monohydrate;ZLN024;YLF-466D;STAT3-IN-1;STAT3 degrader-1;BAY-3827;PM-81I;3α-Hydroxymogrol;Morusin;Nifuroxazide-13C6;AS1810722;α7 nAchR-JAK2-STAT3 agonist 1;HP590;Eupalinolide K;STAT3-IN-11;HTH-01-015;(R)-Reticuline-d3;TMPA;JAK-IN-23;UC-514321
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