Rotigaptide

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Rotigaptide

CAS No. : 355151-12-1

Biological Activity:Rotigaptide (ZP123) is a novel and specific modulator of connexin 43 (Cx43). Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress. Rotigaptide is a potent antiarrhythmic peptide (AAP) with improved stability and has the potential for the investigation of cardiac arrhythmias-specifically atrial fibrillation[2].

Research Area:Cardiovascular Disease

Targets:Gap Junction Protein

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