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Ropivacaine hydrochloride
CAS No. : 98717-15-8
Biological Activity：Ropivacaine hydrochloride is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese[2]. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell’s membrane[3]. Ropivacaine is widely used for neuropathic pain management in vivo.
Research Area：Neurological Disease|Cardiovascular Disease
Targets：Sodium Channel|Potassium Channel
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Drug Repurposing Compound Library;Anti-Cardiovascular Disease Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Alzheimer’s Disease Compound Library;Neuroprotective Compound Library;Anti-Pancreatic Cancer Compound Library;Neurodegenerative Disease-related Compound Library;Mechanoreceptors Compound Library;Rare Diseases Drug Library;Children’s Drug Library;Sodium Channel Blocker Library;Potassium Channel Compound Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;
Related Small Molecules:Lu AE98134;Kv3 modulator 2;Zandatrigine;Veratridine;Brompheniramine-d6 maleate;Pinacidil;GX-674;AMP-PNP tetralithium;Dibucaine;IK1 inhibitor PA-6;VU590;Sodium Channel inhibitor 2;3-Deoxyaconitine;Domiphen bromide;Mesoridazine benzenesulfonate;Tetrandrine;20(S)-Ginsenoside Rg3;(S)-(+)-Modafinic acid-d5;Tocainide hydrochloride;Ketanserin;Licarbazepine-d4-1;Metaflumizone-d4
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