For research use only. We do not sell to patients.

RG108

CAS No. : 48208-26-0

Biological Activity：RG108 (N-Phthalyl-L-tryptophan) is a non-nucleoside DNA methyltransferases (DNMTs) inhibitor (IC₅₀=115 nM) that blocks the DNMTs active site. RG108 (N-Phthalyl-L-tryptophan) causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences^[2]^[3].

Research Area：Cancer

Targets：DNA Methyltransferase

Related Screening Libraries:Bioactive Compound Library Plus;Epigenetics Compound Library;Anti-Cancer Compound Library;Peptidomimetic Library;Reprogramming Compound Library;Anti-Blood Cancer Compound Library;Transcription Factor-Targeted Library;

Related Small Molecules:RSC133;SGI-1027;γ-Oryzanol;Bobcat339;TFMB-(S)-2-HG;Dihydro-5-azacytidine;DC-05;Zebularine;Hinokitiol;2′-Deoxy-5-nitrocytidine;SW155246;GSK-3685032;DC_517;Lomeguatrib;ZIKV-IN-2;O6BTG-octylglucoside;AA-CW236;DY-46-2;Psammaplin A;DNMT3A-IN-2;Nanaomycin A;ZIKV-IN-3;5-Azacytidine;CM-579

About Us:

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
Structurally and synthetically diverse biologically active compounds；
roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；

Structurally and synthetically diverse biologically active compounds；

Customized order volume ranging from milligrams to kilograms scale；

We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.

Top Publications Citing Use of MCE Products